Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines
mRNA vaccines have been administered billions of times worldwide and their importance was underscored by the 2023 Nobel Prize in Physiology or Medicine, awarded to Katalin Karikó and Drew Weissman “for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19”. Nonetheless, mRNA vaccines have been the subject of controversy, some of it rooted in misinformation. For example, false claims and conspiracy theories about mRNA vaccines altering DNA gained traction, spreading fear of long-term…
