Re-engineering of acetyl coenzyme A metabolism prevents senescence in budding yeast
For many, the idea of living forever is unappealing. Even if good health is thrown into the bargain, interest in immortality remains ambivalent. But what if we could stay healthy right up until a timely death? Recent work from the Houseley lab suggests that, at least in budding yeast, healthspan can be extended without also extending lifespan. In a 2023 paper, they showed that a galactose diet suppresses senescence (i.e., loss of fitness) in aging yeast without extending their lifespan. In…